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6082613 [online] Available at: Maeda-Yamamoto, M., Nishimura, M., Kitaichi, N., Nesumi, A., Monobe, M., Nomura, S., Horie, Y., Tachibana, H
This approach improves bioavailability compared to standard oral forms, helping the body utilize glutathione more effectively
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Furthermore, defects in IFN- signaling, often due to loss-of-function mutations in JAK1/2 or STAT1, impair human leukocyte antigen (HLA) upregulation, diminish PD-L1 expression and impede T-cellmediated antitumor responses, thereby conferring resistance to ICB
For biochemical assays, total liver lipids were extracted using chloroform/methanol (21, v/v)
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