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C-terminal assays may be sensitive to species-dependent differences in amidation ratios and, as such, may underestimate the secretion of GLP-1 if targeting glycine-extended GLP-1 forms, which could be true for rats but not mice [22]
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with limited therapeutic options and a profoundly immunosuppressive tumor microenvironment (TME)
Construction of Ob/Ob-GAN NASH Mice and Drug Intervention C57BL/6 mice and ob/ob mice were provided free access to tap water and normal chow until they were 25-week-old
Dissertao de Mestrado, Universidade de So Paulo 2003
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