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It acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme expressed in multiple tissues including adipose tissue and the liver that plays a role in cellular energy metabolism and fat storage

It does not make genetic NNMT knockdown and small-molecule inhibition the same experiment

Chromatographic conditions employ a C18 reversed-phase column, with acetonitrilewater solution (adjusted to an appropriate acidity with phosphoric acid) as the mobile phase

The exact frequency will depend on how your body responds to the treatment and the underlying cause of your deficiency