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Fan, Q.-X
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Preclinical studies have not reported significant adverse effects
Full growth hormone administration can stimulate cortisol production through various mechanisms, and elevated cortisol is well-documented to increase appetite, particularly for high-calorie comfort foods, and promote abdominal fat accumulation
found no significant differences in GH pulse frequency across a 24-hour period between groups with normal GH secretion and those with isolated GHD, noting between eight and eleven GH pulses in both groups
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