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Metabolomic pathway analysis demonstrated that these metabolites are involved in sulfurate amino acids metabolism, with respect to cysteine, and glutathione synthesis (Fig

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The progressive degeneration of neuronal cells that accompanies the decline of memory and other cognitive functions in subjects with Alzheimers disease is associated with an intracellular aggregation of Tau fibrils, an extra-neuronal accumulation of b-amyloid peptides into senile plaques, and an oxidation-reduction (redox) imbalance of complex etiology