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These microspheres themselves trigger a foreign body inflammatory response independent of the medication, which is why exenatide extended-release has the highest injection site reaction rate of any GLP-1 agonist at 16%

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With combinatorial metabolic-targeted agents, it will be imperative that harm to normal tissues is minimized for successful translation to the clinic

Now a newer class of medications used to treat type 2 diabetes has gained attention because of their impressive weight-loss results in many cases, 10% to 20% of a person's body weight

The nitrosative door model presents the bimodal action of RNS in seeds (Krasuska and Gniazdowska 2012