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Clinical supervision that includes source verification is the single most important safety consideration in BPC-157 use
The GH/IGF-1 axis declines with age, and secretagogues can transiently raise it, but restoring a biomarker toward youthful levels has never been shown to equal restored youthful function and some GH-axis interventions carry theoretical risks that make the anti-aging framing particularly premature
A consensus statement from the Growth Hormone Research Society acknowledges that "preclinical data suggest that GH/IGF-I is involved in cancer development." Angiogenesis Concerns: The VEGF/VEGFR2 pathways activated by BPC-157 and other peptides are "active in roughly half of human cancers." While promoting blood vessel formation is beneficial for healing, it's concerning in the context of potential tumor growth
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