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16 17 18 Newly emerging indications for GLP-1 medicationsincluding heart disease, metabolic liver disease, peripheral artery disease, Alzheimers/dementia risk, and even alcohol and substance use disorders, as highlighted in a 2025 study in JAMA 19 suggest these drugs may soon play a much broader role in medicine than just treating diabetes or obesity
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Similarly, nondifferential misclassification of binary exposures and outcomes, as seen in claims data-based studies, tends to bias effect estimates toward the null 44
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AOD-9604 is a synthetic peptide derived from a 15-amino-acid fragment of human growth hormone specifically the C-terminal region spanning residues 176-191 engineered to isolate the fat-metabolizing activity of hGH while leaving out the portions responsible for growth and blood sugar effects
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