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Kidney Issues: Kidney problems, including acute kidney injury, have been reported in a small number of patients, particularly those with pre-existing kidney conditions

There are no theoretical oncologic concerns

Moreover, the inordinate expression of Bax and Bcl-2 was also redressed by H 2 (Qiu et al., 2020)

doi: 10.1056/NEJM199607043350101 Summary Keywords anabolicandrogenic steroids, endocrine disruption, hypogonadism, hypothalamicpituitarygonadal axis, male infertility, testosterone misuse, young men Citation Kowalik K, Harasny P, Kaliczyska L, Reweda-Kwiatkowski K, Starzyski D, Pawlak M, Waloryszak A, Ptak M, Modrzejewski A and Lisman D (2026) Non-medical use of exogenous testosterone and anabolicandrogenic substances in young men: health, psychological, and fertility consequences

By moderately promoting oxidative stress, the antioxidant defense mechanisms of vascular endothelial cells can be activated, reducing the formation of oxidized LDL and thus alleviating the progression of atherosclerosis [197]