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Most community protocols start cagrilintide at 0.25 mg/week once retatrutide is established, then step up every 4 weeks to 0.5, 1.0, 1.7, and 2.4 mg/week
These effects impair oxygen and nutrient delivery to tissues, triggering hypoxia, metabolic acidosis, and organ failure (Higashi et al., 2014
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