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GLP-1 RAs mimic the action of a natural hormone to help regulate blood glucose

Treatment with Nec-1, a well-established necroptosis inhibitor, can inhibit cell death in vitro , and reduce kidney inflammation and attenuate renal dysfunction in HFD/STZ-induced diabetic mice (74)

It activates GLP-1 receptors to support appetite regulation, slower gastric emptying, and improved insulin response, all as part of a physician-supervised plan

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Semaglutide alone does not protect muscle