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Smits MAJ, Schomakers BV, van Weeghel M, Wever EJM, Wst RCI, Dijk F, et al
An increase in SERT expression leads to lower enteric serotonin levels and contributes to constipation-predominant IBS (IBS-C), while a decrease in SERT expression increases serotonin levels in the gut and can be a factor in IBS-D
In preclinical work, Dihexa promoted dendritic spine formation at concentrations reported to be far more potent than BDNF on a molar basis in specific assays [McCoy et al., 2013]
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