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Some show improved markers of mitochondrial efficiency, especially in populations with higher metabolic stresspeople in large deficits, individuals on GLP-1 medications, high-volume endurance athletes, and adults with insulin resistance
Semaglutide often starts affecting appetite before significant weight loss occurs
Some weeks feel strong
Between 36% and 59% of patients in semaglutide groups achieved NASH resolution with no progression of fibrosis (compared to 17% in the placebo group, NCT02970942)
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