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This medications safety profile has not been studied in patients under the age of 18, pregnant and lactating people, or those with normal BMIs. At the time of publishing, the FDA has only approved three GLP-1 agonists for weight loss: Wegovy (semaglutide), Zepbound (tirzepatide), and Saxenda (liraglutide)

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2.12 Cell transfection MCECs or MPMs were seeded in 6-well plates and transfected with siSTAT3 or the corresponding negative controls using Lipofectamine 2000 reagent