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AMG 133 or matching placebo was administered in the morning (fasting) by s.c
Many commercial formulations are stable at room temperature
The cortical and subcortical regions in the SCAN are represented in purple
Importantly, miR-20a-5p inhibits ACSL4-dependent ferroptosis by targeting the 3UTR of ACSL4 mRNA as a negative regulator of ACSL4
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