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When combined with medications such as sodium-glucose cotransporter-2 (SGLT-2) inhibitors or specific insulin formulations that exhibit complementary effects on weight regulation, combination therapy has the potential to significantly enhance weight loss outcomes and improve body composition in patients with co-morbid type 2 diabetes and obesity

If your vial should theoretically contain 4 doses at 75 units, plan for 3.8 effective doses instead

For some patients, this combined effect may decrease overall calorie intake more than intended

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This creates a long-term strategy question