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10.1186/1755-1536-1-6 4 AmicF.DrmicD.BilicZ.KrezicI.ZizekH.PeklicM.et al (2018)
Retinol activates nuclear retinoic acid receptors and drives collagen gene transcription, but frequently causes irritation, peeling, and photosensitivity at therapeutic concentrations
Companies like those developing GLP-1 companion products are exploring various approaches in this space
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