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The PIONEER 2 and 3 trials enrolled patients with diabetes with HbA1c values between 7.0% and 10.5%, and PIONEER 4 enrolled patients with diabetes with HbA1c values between 7.0% and 9.5%

The "worst" timing for nausea-prone individuals tends to be late morning or early afternoon (10 AM to 2 PM), which puts the peak nausea window right at dinner time when food aversion is most problematic

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Personalized guidance from a medical provider can help refine these strategies

But the tirzepatide in your refrigerator right now may have been compounded in their facility before reaching you through a telehealth platform or medical practice