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Fat oxidation ramps up

Treatment decisions depend on provider evaluation and clinical appropriateness

The same trials are also the only window onto long-term safety: what are the implications of the elevated resting heart-rate in patients with heart failure or irregular heartbeats, let alone healthy individuals considering the longer term health implications of these drugs

EI503 comparisons ( Figures 3c, f ), eight DEGs were shared and showed the same trend

However, selective NaV1.7 inhibitors have repeatedly failed in the clinic, and recent studies across multiple programs point to on-target autonomic and cardiovascular liabilities