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Kidney-related complications, including nephrolithiasis and interstitial nephritis, have been reported in comprehensive safety analyses ^36
As shown in Figure 8E , genes related to base excision repair and pyrimidine metabolism, apoptotic process, and ribosome and thermogenesis formed the three main cores of the network
The nasal delivery system ensures rapid absorption and effectiveness, paving the way for advancements in treating metabolic disorders
Its important to note that most of the existing research on chanca piedra has been done in animals or test tubes, using highly concentrated extracts