Metformin, acarbose, empagliflozin, and exenatide were associated with mild weight loss (less than 3.2% of initial weight)
LillyDirect offers Zepbound vials at $299-449/month for self-pay patients
Dosage & Administration ['Adults: 1 effervescent tablet in 200 ml water once daily', 'Drink immediately after dissolving', 'Take on an empty stomach for best absorption', 'Continue for 812 weeks'] Side Effects ['Generally well tolerated', 'Mild GI upset', 'Allergic reaction (rare)', 'Sulfurous taste in some patients'] Contraindications & Precautions ['Hypersensitivity to glutathione or vitamin C', 'G6PD deficiency (caution)', 'Active peptic ulcer'] Storage Store below 25C, keep bottle tightly closed
Retatrutide (Lilly's triple agonist targeting GLP-1, GIP, and glucagon receptors) is showing unprecedented effectiveness plus significant non-scale benefits, including fatty liver reduction but is still years from approval
It isnt the same as VIP and shouldnt be viewed as a direct Shoemaker Protocol replacement, but it may help calm inflammatory input from the gut in some patients